By rethinking the drug delivery devices used with GLP-1s, is it possible to improve adherence and unlock the full potential of GLP-1 therapies
The serine and the two acidic residues make the peptide polar and its behaviour somewhat pH-dependent
Potential Research Applications: Peptide Pathway Modeling Cellular Protein Binding Studies Non-Human Experimental Assays In Vitro Signal Transduction Research All applications are intended for scientific investigation only and not related to clinical or therapeutic use
After the combination of the two drugs, it can inhibit the function of two drug pumps (P-gp and PTCH1) by targeting the ABCB1 and Hedgehog pathways, increase the intracellular concentration of cisplatin, and improve the sensitivity of cancer cells to cisplatin
Synthesis conditions: The entire synthesis process needs to be carried out under suitable environment and conditions, such as temperature, pH value, reaction time, etc., which need to be strictly controlled to ensure the smooth progress of the reaction and the quality of the product
34: 135143 (2011) Sakamoto K, Tonooka M, Abe K, Usami K, Kasahara T
