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While it can begin at any stage of perimenopause or menopause, it usually moves through different stages

A 2024 study (Grilo et al., Obesity 2024) found that patients with BED on GLP-1 medications had higher discontinuation rates (38% vs 22%) and more rapid weight regain after stopping compared to patients without BED

The results are also supported by a meta-analysis considering only data from subjects not receiving metformin at baseline in the HARMONY-OUTCOMES and LEADER trials, which found that GLP-1RAs are effective at reducing CV risk in metformin-nave subjects [25]

market background , a region where growth has slowed notably

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