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(PubMed) Zimmermann MB, Galetti V

Dehydration exacerbates constipation, headaches, and fatigue

These combined factors result in the contamination of freshwater resources, which subsequently acts as a critical vector for exposure in both wildlife and humans through the ingestion of contaminated water and the food chain 6

Constipation: Counterintuitively, also common, especially with higher doses of tirzepatide and retatrutide

10.3390/antiox14030320 33 ChenH.YangT.ChenJ.ChenL.DaiY.ZhangJ.et al (2021)