With BPC 157 administration, these beneficial effects were combined with particular specificities with the altered genes expression ( Egr, Nos, Srf, Vegr, Plc , and Kras ) or no change ( Akt1 continuously remained unchanged) (Vukojevic et al., 2018)
Combining microneedling with topical GHK-Cu is a logical protocol you're getting the mechanical stimulation benefit and improving delivery simultaneously
Clamp AR, Schffski P, Valle JW, Wilson RH, Marreaud S, Govaerts AS et al (2008) A phase I and pharmacokinetic study of OSI-7904L, a liposomal thymidylate synthase inhibitor in combination with oxaliplatin in patients with advanced colorectal cancer
Similarly, TB-500 has undergone extensive safety evaluation including human research trials showing safety at intravenous doses up to 1,260 mg equivalent, with no dose-limiting toxicities or serious adverse events attributable to the peptide in carefully controlled studies
Having said that, sulfur sensitive people need to take heed if you are going to use this patch, your sulfur intolerance will EXPLODE unless you take measures to keep it low
GH plays a role in dermal thickness and collagen biosynthesis, reversing age-related skin changes (Laron, Pediatric Endocrinology Reviews )
