It may be wise to consider supporting compounds that don't directly contribute to the primary goal but support overall systemic function
Del Prato, S., Kahn, S
Laura has a talent for taking nutritional research and explaining it so that its easy to understand for non-science folk
These events were generally mild to moderate in severity and included: Nausea often accompanying changes in bowel habits, particularly after dose escalation Diarrhoea loose or watery stools, sometimes with urgency Vomiting less common but reported, especially at higher doses Constipation occurring in some individuals, reflecting the variable effect on gut motility Abdominal discomfort or bloating a sensation of fullness or cramping Flatulence increased wind, which can accompany altered digestion Gastrointestinal adverse events were the most common reason for discontinuation in the Phase 2 trial, occurring in approximately 510% of participants depending on dose group
Inclusion criteria were as follows: Age 65 years with T2DM (according to ADA guidelines), Body mass index (BMI) 24kg/m, with no prior use of GLP-1RA or DPP-4 inhibitors
Mol Cell Biochem 431:197210 Casey A, Greenhaff PL (2000) Does dietary creatine supplementation play a role in skeletal muscle metabolism and performance