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Gain in MET copy number is present in almost 16% of the HNSCC patients and associated with an increased c-MET expression and poorer outcome [87]
This change in eating behavior is instrumental in achieving sustainable weight loss
Healthcare systems and patients are becoming more proactive in seeking treatments that facilitate sustainable weight loss and help reduce obesity-related complications, giving Saxenda a strong advantage as a recognized solution in this domain
Indeed, in the cardiovascular outcome trial (CVOT) for semaglutide, SUSTAIN 6 a relatively short (two-year) and small (3,297 individuals) preregistration trial (an extensive CVOT in obese individuals without T2DM (SELECT) is expected to complete in 2024) HbA 1c was powerfully and durably reduced
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