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In proof-of-concept studies, NNMT inhibitors (NNMTis) have demonstrated promise as potential treatments for obesity and obesity-related metabolic comorbidities (e.g., T2D, fatty liver) 8,9,13

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Inhibition of Leukotriene B4-Induced CD11B/CD18 (Mac-1) Expression by BIIL 284, a New Long Acting LTB4 Receptor Antagonist, in Patients With Rheumatoid Arthritis