52 Koyama, K., Usami, T., Takeuchi, O., Morozumi, K
Can be taken orally for gut issues or injected for injury recovery
Skip alcohol 24 hours before your appointment
It increases growth hormone receptor expression in tendon fibroblasts at both mRNA and protein levels, with effects lasting at least three days
QD community oral or SC MOTS-c Daily SC, often 5 days on / 2 off AOD-9604 Daily SC Attribute Max studied dose SLU-PP-332 50 mg/kg BID (mouse, 28 days) MOTS-c 5-15 mg/kg (mouse) AOD-9604 1-5 mg/day in human Phase 2 Attribute Peak efficacy signal SLU-PP-332 ~25-30% fat-mass reduction in DIO mice over 28 days MOTS-c Improved insulin sensitivity in aged mice AOD-9604 Modest fat-loss signal in human Phase 2
Used during a defined recovery window, they are a high-leverage tool