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In general, angiogenesis, the formation of new vessels from pre-existing ones, consists of an orderly sequence of events triggered by growth factors secreted from the surrounding hypoxic tissue (19)
Oral administration of liposome-embedded SOD (L-SOD) could ameliorate oxidative damage and inflammatory responses via inhibition of myeloperoxidase (MPO) and pro-inflammatory cytokines, as well as protect gut barrier function by promoting the expression of the tight junction proteins occludin and zonula occluden (ZO)-1 in the colon 750
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Method: Sprague Dawley rats weighing 200-250 grams were used for the study