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Zepbound has been studied extensively, and compounded tirzepatide has not Clinical trials for Zepbound enrolled over 5,000 participants across multiple studies, tracking weight loss, side effects, dosing schedules, and long-term outcomes over 72 weeks

Individuals who follow a vegan or vegetarian diet or those with absorption issues are particularly at risk and may benefit from B12 injections to maintain optimal levels

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Furthermore, among responders, the weight reduction was generally lower for patients with type 2 diabetes compared to those without diabetes (-8.5% versus -10.8 after 56 weeks)

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