Perrine, S
At the recommended 10mg / 2 ml mix (5 mg/ml): 0.5 mg = 10 units, 1.0 mg = 20 units, 1.5 mg = 30 units, 2.0 mg = 40 units
The Phase 2 trial reference point The Phase 2 retatrutide trial (Jastreboff et al., New England Journal of Medicine 2023) enrolled 338 adults across placebo and retatrutide arms at 1, 4, 8, and 12 mg weekly
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For adults, this results in 14.9 g of B12 absorbed per week