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Out of the 98 G6PD-associated genes that were identified, the five most frequently cited genes were GSR, INS, CAT, SOD1 and ADA

By inhibiting the activity of the inhibitory kappa B kinase (IKK), curcumin prevents the translocation and activation of NF-B, thereby reducing the expression of chemokines and pro-inflammatory cytokines such as TNF-, IL-1 and IL-6, which ultimately attenuates inflammatory responses (Jobin et al., 1999)

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However, a significant trend of weight regain begins just eight weeks after discontinuing treatment and continues over the following months