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Additionally, glutathione plays a crucial role in the detoxification process by conjugating with toxic compounds, making them more soluble and easier for the body to excrete

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For example, FSP1 is an NAD(P)H-dependent oxidoreductase that has long been regarded as a proapoptotic factor that synergistically triggers apoptosis with 4-hydroxy-2-none under oxidative stress conditions [279]

Concerted action of sulfiredoxin and peroxiredoxin I protects against alcohol-induced oxidative injury in mouse liver

The control of ROS involves the glutathione (GSH) balance, owing to antioxidant activity