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Safety and Provider Guidance: Who Should Monitor Tirzepatide Duration Effects Patients on tirzepatide should have baseline and periodic assessments of renal function, particularly if they have preexisting kidney disease or take medications affecting filtration

which is based primarily on data from the SURMOUNT-1 and SURMOUNT-2 studies

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In short: GLP-1/GIP therapies improve body composition , helping you lose fat while maintaining and often improving your lean-mass ratio and muscle function