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This provides a complete picture of metabolic health before compound introduction
[3] Orforglipron was approved for medical use in the United States in April 2026
All Medicare contracted health plans are required by the Centers for Medicare Services to use the U.S
Similarly, the other major Australian guideline, the Living Evidence for Diabetes Consortium: Australian Evidence-Based Clinical Guidelines for Diabetes also advocates for the use of SGLT-2 inhibitors as the first option after metformin (and before GLP-1RA), especially if the patient also has CV disease, multiple CV risk factors and/or kidney disease
All adjustments, nutrition-based ones included, are done as often as needed to maximize results based on feedback, progress pictures, and weight updates