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Research has found that stress hormones impair the production of glutathione in the mitochondrial by dramatically increasing mitochondrial oxygen consumption and reactive oxygen species formation or by increasing glutathione exchange between mitochondria and the cytosol

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[DOI] [PMC free article] [PubMed] [Google Scholar] 155.Marui T., Funatogawa I., Koishi S., Yamamoto K., Matsumoto H., Hashimoto O., Jinde S., Nishida H., Sugiyama T., Kasai K., Watanabe K., Kano Y., Kato N

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Immune-mediated tubule atrophy promotes acute kidney injury to chronic kidney disease transition