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Sleep timing, nighttime awakenings, and morning alertness are common markers to monitor.

You never addressed the root cause

The diffuse pigmentation in Case 1, extending across both upper and lower gingiva, may suggest racial or physiologic pigmentation, drug-induced melanosis, or post-inflammatory hyperpigmentation, particularly in populations with increased melanin deposition

Traditionally, G6PD-d has been studied in the context of RBC hemolysis secondary to ingestion of drugs or foods that cause oxidative stress