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Strategies to Minimize Weight Rebound Beyond Medication While continuous GLP-1 therapy is the most evidence-supported approach, behavioral and lifestyle strategies amplify results

In theory, targeting two different metabolic pathways could provide a synergistic effect

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For instance, improved metabolic health and weight loss achieved through GLP-1 receptor agonist therapy might secondarily influence neurotransmitter balance through reduced systemic inflammation or improved insulin sensitivity in the brain