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The reactions were incubated at 42 C for 2 min, 20 C for 5 min, 25 C for 5 min, 30 C for 5 min, 35 C for 5 min, 37 C for 5 min, 42 C for 45 min, and 2 min at 94 C

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This pre-dosed 1000mg / 3ml pen format ensures convenience, accuracy, and safety during research handling