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So, it would be useful to see what age groups getting onto these drugs are developing acne. For patients who are on the medication and develop acne, but are advised against stopping the GLP-1RAs, Dr Kadam had this advice: Optimise topical acne treatment, encourage good skin hygiene, avoid any potential food triggers and reserve systemic medications for refractory cases. Journal of the American Academy of Dermatology 2025, online 7 February

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Under these conditions, activation of PDH facilitates pyruvate oxidation, attenuates lactate accumulation and restores the NAD+/NADH equilibrium (86)