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Red and yellow circles indicate localized GLP-1 receptor mRNA transcription Activation of incretin receptors initiates a cascade of neuroprotective effects: Improved brain insulin signaling, correcting neuronal energy deficits

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You may notice an increase in appetite and a return of food cravings, allowing you to eat more without feeling as full

For a patient weighing 220 pounds, semaglutide might produce 22-33 pounds of weight loss, while tirzepatide might achieve 33-48 pounds