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There have been few studies on the mechanism of radiation-induced MPNST, where they found that loss of H3K27me3 expression is a highly sensitive marker for both sporadic and radiation-induced MPNST [25], implying that the post-radiation MPNST may share the same mechanism pathway as sporadic MPNST to some extent

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K., Lysiuk, R., Antonyak, H., Noor, S., Akram, M., Smetanina, K., Piscopo, S., Upyr, T., & Peana, M