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Additional authors include Sofiya Matsekyo and Heribert Schunkert

And for the pharmaceutical giants behind WEGOVY and ZEPBOUND, two of the best-selling drugs in modern history, the oral revolution is both their biggest opportunity and their greatest competitive threat

While this drives appetite suppression and weight loss, it can also disrupt normal bowel patterns

The risk of bias assessment indicated that all studies had a good quality

The information above is sourced from the company's published FAQ and does not replace individualized medical guidance from the evaluating clinician

There is insufficient information to draw any conclusions, however DPP4is use in T2DM patients with additional functional hypogonadism is plausible, with caution on their use in male subjects of reproductive age