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We posit that acetylation events are likely affected in these other biological scenarios such as IDH1/2 mutations where KG is depleted

The resulting pressure differential also pulls contaminants back through the needle tract on every subsequent draw, increasing microbial load over the vial's lifespan

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Garber A., Henry R., Ratner R., Garca-Hernndez P.A., Rodrguez-Pattzi H., Olvera-lvarez I., et al