Martin Holst Lange, Executive Vice President for Development at Novo Nordisk, stated, These data reinforce the comprehensive set of health benefits of semaglutide, making it a strong option for healthcare professionals addressing the spectrum of metabolic and cardiovascular health. The SOUL trial confirmed the established safety and tolerability of oral semaglutide, with no new safety concerns identified and long-term safety data covering over 33 million patient years
Specifically, GSH levels returned to their control values, which agreed with the cell-free-based antioxidant activity assays in our previous results 48
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doi: 10.1056/NEJMoa1901118 25 HviidA
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Rare but serious risks include pancreatitis symptoms (severe abdominal pain), gallbladder issues, and thyroid concerns in susceptible individuals