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FFP contains ACE, hence its proposed mechanism in ACE inhibitor-induced angioedema is the replacement of ACE which can subsequently break down Bradykinin to inactive metabolites

While renal function is the primary safety determinant, genetic variants in GLP-1 receptor and related metabolic pathways may help provide context on how your body responds to GLP-1 therapy, which can be interpreted with your healthcare provider to refine treatment selection

Contact your GP or NHS 111 if diarrhoea persists beyond 7 days or if you're passing more than 6 loose stools daily

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