Figure 1 2.1 Overproduction of ROS One hallmark feature of IBD is the overproduction of ROS, which causes dysregulation of signal transduction, an inflammatory response, and DNA damage, all of which contribute to the progression and deterioration of the disease ( 2), nitric oxide (NO), hydroxyl radical (-0H), hydroperoxyl radical (O 2 H), hydrogen peroxide (H 2 O 2 ), and singlet oxygen ( 2.2 Damage to biomolecules ROS can damage various cell biomolecules, including lipids, proteins, and DNA
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During thawing, local concentration gradients and interfacial stress promote aggregation of peptide chains
Its bioactive compounds, particularly 6-gingerol, have been shown to impact gut microbiota and enhance the activity of probiotics, thereby improving the regulation of immune responses in SLE