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It works through a unique mechanism involving the activation of two different types of receptors in the body: the glucagon-like peptide-1 (GLP-1) receptor and the glucose-dependent insulinotropic polypeptide (GIP) receptor

Kidney function is particularly significant for people with diabetes, as high blood sugar over time can damage the kidneys, a condition known as diabetic nephropathy

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Less common side effects during longer trials include: darkening of lips, increase in the number of freckles, darkening of freckles, and increased libido in females

All reagents and chemicals were of analytical grade and used as received without further purification