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Metformin is not a GLP-1 drug it is in a class of medications called biguanides

In this study, patients who took semaglutide lost an average of 14.9% of their body weight over 68 weeks, compared to just 2.4% for patients who received a placebo

Lancet 370(9605):21032111 Wick W et al (2017) Lomustine and bevacizumab in progressive glioblastoma