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Nodules are expected with BPC-157: small subcutaneous bumps at the injection site are a normal depot response, not infection, and resolve within two to three days without intervention

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There is no UK Summary of Product Characteristics (SmPC) for retatrutide, and no authorised clinical dosing or reconstitution guidance exists

In a recent phase I study, retatrutide, a triple glucagon/GIP/GLP-1 receptor agonist, significantly reduced body weight and improved glycemic control, exhibiting a safety and tolerability profile similar to other incretin formulations in study participants, and body weight continued to decrease steadily after a single dose until the end of the study [105] (Figure 6)