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The high prevalence of GI events and differences in safety profiles between the GLP-1 RAs found in this real-world analysis should inform several aspects of clinical practice

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5 grams is the standard prescription, but some data have shown higher doses, particularly for larger people, to have additional benefits, but may worsen side effects like gas, bloating, or upset stomach

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Other foods and habits to be mindful of include: Large portion sizes even of healthy foods, as the stomach empties slowly and overeating can cause significant discomfort Spicy foods evidence is limited, but some people find these worsen gastrointestinal symptoms