Tolerance and adaptation: Because it alters brain plasticity, repeated exposure may create unpredictable long-term changes
Patients with a history of MTC, MEN2, active pancreatitis, or prior severe GI intolerance to GLP-1-based therapy are contraindicated or require careful risk-benefit analysis
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In such environments, M.tb switches to fatty acid metabolism to enter a persistent state
If you use a continuous glucose monitor (CGM), set tighter alert ranges during weeks 3 to 6 to catch unexpected spikes early
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