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Int J Hum Rights Healthc 15:1730 Asano Y, Hiramoto T, Nishino R, Aiba Y, Kimura T, Yoshihara K, Koga Y, Sudo N (2012) Critical role of gut microbiota in the production of biologically active, free catecholamines in the gut lumen of mice

Dosing is the foundation: too little wastes time and money, too much introduces unnecessary risk

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Clinical trials confirmed no effect on serum IGF-1, no negative impact on carbohydrate metabolism, and excellent tolerability with safety profile indistinguishable from placebo