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In the present study, liraglutide effectively inhibited PFKFB3-driven glycolysis in TGF-1 + IL-1-stimulated fibroblasts and silica-induced fibrotic lungs, as well as the enhancement of mitochondrial oxidative phosphorylation in fibroblasts, indicating that activating GLP-1R was sufficient to maintain metabolic homeostasis during pulmonary fibrosis

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The overall RR for pancreatitis was 1.60, and the 95% CI ranged from 0.25 to 11.00, while the overall RR for pancreatic cancer was 0.79, and the 95% CI ranged from 0.26 to 2.40