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Innovative Therapy with Stem Cell-Derived Extracellular Vesicles on Cardiac Hypertrophy in an Animal Model of Atherosclerosis

The ferroptosis inhibitor liproxstatin-1 has been shown to reverse iron accumulation, endothelial damage, and increased atherosclerosis in Jak2VF chimeric mice and VFEpoR mice, 539 indicating a potential therapeutic target for mitigating erythrocytic ferroptosis-mediated cardiovascular risk

Collagen is secreted by connective tissue cells, where it forms the structural part of the extracellular matrix

Di Domenico EG, Rimoldi SG, Cavallo I, DAgosto G, Trento E, Cagnoni G, et al

P.et al (2022a)

It is worth that anti-cancer therapy development, even all pharmaceutical developments, represents a multi-disciplinary coordination from fundamental science, physicians to pharmaceutical industries, and requires mount of investment resources