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Drop back to the previous dose level and extend the duration at that dose before attempting escalation again

It should only be used under the guidance of a licensed medical provider who can evaluate your health, order lab work, and monitor your progress

doi: 10.1172/jci.insight.174825

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Large differences in the biological half-life and volume of distribution of hydrochlorothiazide in normal subjects from eleven studies

The intervention reduced plasma and erythrocyte lipid peroxidation levels, while increasing plasma vitamins A and E, reduced glutathione (GSH), and GPx activity