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The combined treatment downregulates the activity of the anti-apoptotic molecule Bcl-2, upregulates the expression of the pro-apoptotic molecules P53 and Bax, and increases the activity of caspases to promote endogenous apoptosis
In addition to Hyaluronic Acid fillers (Restalyne, Juvederm), biostimulatory fillers such as poly-L-lactic acid (Sculptra) lead to prolonged effects from collagen production
Buhr RG, Barjaktarevic IZ, Quibrera PM, et al
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Every ingredient in the formula has a clear, scientifically supported role
