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As the new obesity pharmacotherapies will lead up to 1525% mean WL, intensive lifestyle interventions may provide small additional WL benefit to these treatments [11, 106]

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Frequent and accurate monitoring is especially important with these patients given that there may be significant underlying anatomical changes over time (in addition to treatment-related alterations)

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Of interest, in the group of streptozocin-induced diabetic rats, the treatment with Ex4 reduced inflammation and fibrosis both in the ovary and endometrium, with associated decrease in inflammatory and oxidative stress markers, and increased ovarian reserve

Its value is summed up by Mojsov who called it a tour de force