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Clin Pharmacokinet 30:359371 Tucker GT, Casey C, Phillips PJ, Connor H, Ward JD, Woods HF (1981) Metformin kinetics in healthy subjects and in patients with diabetes mellitus

Exendin-4 shares only 53% amino acid sequence identity with human GLP-1, and that difference turned out to be everything

For individuals with metabolic dysfunction-associated steatotic liver disease, formerly called non-alcoholic fatty liver disease, that difference could mean the gap between disease progression and reversal

When to Seek Medical Attention If you experience severe abdominal pain, persistent vomiting, or signs of dehydration while on GLP-1 therapy, contact your physician immediately

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