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Both achieve approximately 20% weight reduction, making them the most effective anti-obesity pharmacotherapies

SIDE EFFECTS: Weight gain, diarrhea, and joint pain may occur

Aside from serotonin, tryptophan is catabolized into several other neuroactive compounds, including the neurotoxic kynurenine (KYN) and the neuroprotective kynurenic acid (KYNA) (Figure 3)

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Radiology 258 , 174181 (2011)