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[3] Conversely, rapid administration IV has occasionally caused hypotension or fainting, possibly from vasovagal responses or histamine release

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Comparative analysis with other antioxidant peptides and molecules suggested that GHK might indicate a higher relative affinity for hydroxyl radical neutralization under laboratory settings

PMID 34405378

Tropolone, another tyrosinase inhibitor that has been studied, was also found at the entrance of the active site of mushroom tyrosinase and exhibited mixed inhibition mode similar to KA 41,42