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The clustering RMSD values were set to 1.5 as suggested by the server for protein-ligand docking (Sangeet and Khan 2020

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The result at week 88: Continued tirzepatide: :Lost an additional 5.5% of body weight (total loss from baseline: ~25%) Switched to placebo: Regained 14.0% of body weight (net loss from baseline: ~9%) A 19-point swing between continued and discontinued groups