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In the central nervous system, particularly the hypothalamus and the area postrema, GLP-1R activation suppresses appetite and enhances satiety

For expression of a roGFP2- Ec DsbA(SP) fusion protein, a truncated variant of the dsbA ( nt1-48 ) gene was PCR amplified lacking the periplasmic sequence (SP)

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They can also help treat B12 deficiency

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