Results We show that our model accurately reproduces published clinical and experimental data on the dose-dependent time course of acetaminophen in the plasma, the accumulation of acetaminophen and its metabolites in the urine, and the depletion of glutathione caused by conjugation with the toxic product
During stress, arginine plays a critical role in the synthesis of NO, a signalling molecule that regulates vascular tone, blood flow, and immune responses [31]
N., de Wet, W
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