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If worsening: Add topical lidocaine for the most affected areas

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Patients with certain GLP1R variants may require lower starting doses of tirzepatide to minimize nausea while on beta-blockers, whereas others tolerate standard doses without issue

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Green tea phytosome Studies 18 Di Pierro F, Menghi AB, Barreca A, Lucarelli M, Calandrelli A