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However, due to the limited data collected on mitochondrial metabolism, the results presented here should be considered as preliminary, providing a basis for further studies in animal models and clinical samples, supporting the hypothesis that irisin may mediate the action of GLP-1RAs

In the central nervous system, pramlintide acts on the area postrema and hypothalamic satiety centers to promote feelings of fullness and reduce food intake through episodic satiety signaling, contributing to body weight reduction over chronic use

Bupropion can raise blood pressure, an effect seen in roughly 6% of users

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Burrin DG, Stoll B, Guan X, Cui L, Chang X, Hadsell D

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