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Clinical Global Impressions (CGI) Scale This brief, 3-item assessment tool provides a global rating of illness severity (CGI-S), global improvement or change (CGI-I), and therapeutic efficacy (CGI-E)

No unpublished data, insider access, or brand-provided samples informed this review

Melasma primarily affects the face and occurs symmetrically on the cheeks, bridge of the nose, forehead, chin, and above the upper lip

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It has been soaked in a highly concentrated essence based on: guaiazulene, Roman chamomile oil, shea butter, macadamia oil, trehalose and hyaluronic acid