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Expansion of myeloid-derived suppressor cells with aging in the bone marrow of mice through a NF-B-dependent mechanism

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Nitrosylation of cystein 10 promotes dsNNTTR formation Our results demonstrate that nitrosative thiol modification efficiently promotes intermolecular disulfide bond formation in TTR, as evidenced by the prominent dsNNTTR dimer observed by non-reducing SDSPAGE following GSNO treatment