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In Vitro and Ex Vivo Evidence (Moderate-Strong) The strongest mechanistic data comes from cell culture and organ culture studies

This is especially important since serums are typically lighter than creams

The interaction between FOXO4 and p53 within the nucleus plays a crucial role in the survival of both normal and senescent cancer cells 25,34

In the control group, in which dividing and senescent cells were treated with DMSO, no caspase 3/7 activity was detected (Figure

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