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The test identifies genetic variants in your GLP1R, GIPR, FTO, and MC4R genesall of which influence how your body responds to semaglutide and whether you might benefit from a different peptide compound

Circulation Research

Theranostics 9 , 38403852 (2019)

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Trypsin would normally cleave at Lys or Arg, but Lys26 is blocked by the lipid, so tryptic digestion yields large fragments